JAK2 Aberrations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia
نویسندگان
چکیده
منابع مشابه
JAK2 aberrations in childhood B-cell precursor acute lymphoblastic leukemia
JAK2 abnormalities may serve as target for precision medicines in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). In the current study we performed a screening for JAK2 mutations and translocations, analyzed the clinical outcome and studied the efficacy of two JAK inhibitors in primary BCP-ALL cells. Importantly, we identify a number of limitations of JAK inhibitor therapy. J...
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ژورنال
عنوان ژورنال: Blood
سال: 2016
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v128.22.583.583